A team of Japanese researchers and scientists are working on a groundbreaking drug that has successfully grown new teeth in animal tests, and are now planning to start clinical trials on humans. The pharmaceutical startup Toregem Biopharma, funded by Kyoto University, is set to begin trials next year in order to confirm the drug’s safety. Their goal is to have the drug on the market by 2030.
The drug works by inhibiting the protein that suppresses tooth growth, thereby stimulating the growth of “tooth buds” that are already present in the gums. Tests on mice, ferrets, and dogs have shown promising results. The researchers hope to initially treat patients with congenital tooth loss, who are unable to grow teeth due to genetic issues. They also hope to address tooth loss caused by cavities and other dental problems.
This development could be a game-changer for individuals who have lost teeth. Instead of relying on dental implants or dentures, this drug could potentially provide a natural and permanent solution. Not only would this improve functionality and aesthetics, but it could also have a positive impact on an individual’s overall oral health.
The upcoming clinical trials will be crucial in determining the drug’s safety and effectiveness in humans. If successful, it could revolutionize the field of dentistry and change the way tooth loss is treated. It is an exciting prospect for both researchers and individuals who have experienced tooth loss.
Sources:
– The Japan Times: https://www.japantimes.co.jp/news/2022/09/27/business/science-health/japan-grow-teeth-drug/
– Scrippsnews.com: [No URL provided]
Definitions:
– Tooth buds: The early stage of teeth development, located in the gums.
– Clinical trials: Research studies conducted on humans to evaluate the safety and effectiveness of new medical treatments or interventions.