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Home - Cover Story - Article

From Good to Better: Critical Care

Technology has permeated every aspect of critical care


Dr KJ Choudhury

Intensive care is nothing but intensive monitoring. We have come a long way from recording clinical vital signs like pulse, blood pressure (BP), temperature and respiration and now pain as the fifth vital sign. Technology has permeated in almost every aspect and critical care is no exception. Everything could be done manually, but soon it was discovered that we need advanced technologies to replace the old ideas. Some of these monitoring technologies were used in the operating theatre and they were extended to the ICU. Very soon, it was realised that critically ill patients require continuous and effective monitoring of all vital signs which was considered impossible a few years earlier. The sense of urgency created by critically ill patients combined with readily visible success and failure drives the quest for improved monitoring and therapeutic tools. We shall discuss some of these developments briefly.

Area of Diagnostics

Point-of-care (POC) testing refers to the performance of diagnostic tests at either directly at the patient's bedside or in a 'mini' or 'stat' laboratory within the ICU setting. Therapeutic Turn-Around Time (TTAT) is the time between ordering the tests to the implementation of the actions generated by the results. Multi-step central laboratory programme leads to long delays and may not keep pace with the dynamically evolving clinical needs of the unstable, critically ill patient and often had to be repeated because of error in sampling, labeling, or inadequate sampling. When laboratory results arrive at the ICU, they reflect the past and not the patient's present condition. These can definitely change the outcome of the critically sick patients with rapidly changing internal milieu. Analysis of serum electrolytes is an example, reports of which, if not available immediately, will be useless in terms of replacement therapy. A haemodynamically unstable patient loses consciousness within ten seconds of oxygen (O2) deprivation and within six minutes permanent brain damage can result due to drained creatine phosphate and adenosine triphosphate (ATP) energy reserves. With the availability of bedside multi-analysers, critical care profile (CCP) should suggest whether tissues are receiving adequate oxygen or not, and why the availability has been compromised.

Today, technological advancement characterised by microchemistry, micro computerisation, miniaturisation and non-invasive testing has revolutionised the concept of present day laboratories. A blood monitor can be used ex vivo or in vivo. Ex vivo technologies use specimen that are drawn from the patient and analysed outside the body, with some of them allowing the return of the specimen to the patient. In vivo technologies provide the opportunity to measure pH, blood gases, electrolytes, lactate, and glucose levels directly, gastric intramucosal pH, with the help of invasive sensors. Advanced IT systems also are playing an increasingly important role. POC testing, by making test results rapidly available to clinical information systems through electronic patient records. With the ever decreasing blood sample requirements for analysis, microsample POC devices can have a great impact on blood conservation.

Integration of IT with ICU

Physiological signals are complex and noisy and patients respond to therapies in highly individual ways. Hence, the challenges of improved continuous monitoring remain. Enormous amount of data is created in ICU from ventilators to assist breathing, intravenous (IV) lines for fluids, medications and nutrition, and a multitude of monitors, most of them controlled by small but powerful computers and from large variety of laboratory studies and imaging. IT makes it possible to automatically collect, process, retrieve, analyse patient data from variety of equipment and sources that will help improve clinical decision, productivity as well as reduce medical errors. Taking efficiency in monitoring trends, computer decision support technique has been devised resulting in a reduction in false positive alarms and time required for correct diagnosis of life threatening conditions in the ICU.

Future is Intelligent
Currently, the vital sign monitors tell the intensivists about the critical changes that have already occurred. Future intelligent monitors will be able to warn the caregivers much ahead of occurrence of actual critical events. The monitor would in fact be able to sense warning of critical events rather than present. Continuous monitoring of changes occurring at cellular level in a critically ill patient is feasible today. Developments are occurring in this area like brain O2 monitor. Trends of monitoring are more in favor of non-invasive techniques which will eliminate cumbersome invasive procedure that requires lot of skills.

Target-oriented drug delivery systems are being developed to reduce both, dose and toxicity of potent drugs. Some of the systems delivering drugs like insulin can adjust the dose by sensing blood glucose level.

Life-saving equipment is being developed which are sensitive to changes in patient's vital functions and automatically adjusts the settings according to patient needs. Many of mechanical ventilators today are already patient sensitive.

Like any other field of science the technology used in critical care medicine is evolving very fast. So the person/ man behind the machine must keep pace with latest development and provide feedback for continuous improvement.

Interpretation of information overload may be time consuming and error prone. On the other hand, the richness and details of data could be of immense help to the clinicians through systems that translate medical device data into industry standard formats that can communicate with modern clinical information systems. This can even replace all paper forms by an electronic equivalent, resulting in a paperless ICU.

There is also the need for these processed data to be available to the physician anywhere, both inside and outside the hospital through software that supports bi-directional sharing of medical information between patients and physicians. As matter of fact, softwares are available that enables the physician to access real time patient data from anywhere who further can issue necessary instruction to the immediate care givers using two way communications.

The writer is Senior Consultant Neuroanesthesiology & Pain Management Indraprastha Apollo Hospital New Delhi
E-mail: kjchoudhury@samvedana.org

 


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