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Winning The War On Pain
Interventional pain management procedures and techniques
have evolved as a new speciality in India, finds out Shardul Nautiyal
Pain is not just a symptom demanding our compassion,
it can be an aggressive disease that damages the nervous system: Gary Bennett
With
minimally invasive interventional pain management procedures taking over the
conventional techniques, less hospitalisation, less morbidity, better patient
outcome along with patient satisfaction have brought about a paradigm shift
in pain management techniques. Interventional pain management procedures have
evolved as a new speciality in India. Statistics from advanced countries show
that 15-20 per cent of population have acute pain (medical and surgical emergencies,
postoperative pain, after accidents and injuries) and 25-30 per cent of all
population have chronic pain (chronic backache, cancer pain, migraines, arthritis
or neuropathic pain). Because it impairs the ability to work and have a productive
life, pain has serious economic and social consequences. Mild pain erodes the
reserves of capability to work or to relax, altering the quality of life.
Paradigm Shift
"Pain is a more terrible lord of mankind than even death itself,"
said Nobel laureate Albert Schweitzer in 1931. This forms the opening sentence
of the classic textbook Bonica's management of pain in 1953. Today, proper management
of pain remains one of the most important and pressing responsibilities of medical
institutes. Technology has a major role to play in the development of various
interventional modalities of pain management. The WHO theme that 'Pain relief
should be a human right' has also helped in developing newer modalities of pain
relief from a simple headache to severe pain in a cancer patient. There has
been much academic activity, pain conferences and sessions on pain management
in conferences of other specialities. For instance, Samvedana Hospital and Indian
Society for Pain Research and Therapy are organising an international pain conference
on a common medical problem 'chronic pelvic pain' this year.
Interventional pain procedures have long been performed but in a very limited
way because of lack of equipment like image intensifier and neglect by authorities.
Interventional Procedures Vs Surgery
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"Specific
drugs will replace the present crop of painkiller medications"
- Dr KJ Choudhary
Senior Consultant
Pain Management
Indraprastha Apollo Hospital,
New Delhi
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According to Dr KJ Choudhary, Senior Consultant, Pain Management,
Indraprastha Apollo Hospital, New Delhi, "A young man with intractable
low back pain, unresponsive to conservative treatment will end up getting an
MRI done, which will show a disc protrusion or prolapse (which may not necessarily
be the cause of his pain) and end up in surgery. But if he approaches a specialised
pain management physician, he will try to find out the locus of the pain generator,
which may be in the muscles (myofacial pain-very common) or disc (confirmed
by provocative discography), sacroiliac joint, facet joint, spinal canal stenosis
or spinal nerve root compression due to narrowing."
Ninety percent of pain-related surgery can be avoided with the help of interventional
pain management procedures. And 95 per cent of cases are of day care. Cost is
substantially less in interventional procedure compared with surgery. The procedures
can be repeated without major morbidity. Return to work is also almost immediate.
"Interventional pain management is a multi-disciplinary approach, orchestrated
by a dedicated team of pain management specialists, anaesthetists, nurses and
surgeons," explains Dr Kailash Kothari, Pain Management Specialist, Swastik
Hospital, Mumbai.
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"As
such surgery is to be performed only when specifically indicated"
- Dr Lakshmi Vas
Pain Management Specialist
Ashirwad Pain Relief Clinic,
Mumbai
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Surgery is a powerful tool in the treatment of disease, be
it cancer, infections, orthopaedic or spine problems. However, it has specific
indications, and as an invasive treatment has many anticipated problems. "As
such surgery is to be performed only where it is specifically indicated. For
example, a patient with motor weakness and back pain may need surgery to relieve
pressure on his spinal cord rather than a block to relieve pain," says
Dr Lakshmi Vas, Pain Management Specialist, Ashirwad Pain Relief Clinic, Mumbai.
Similarly, a patient without any motor problems would benefit more from a block
than from surgery. "It is binding on both the surgeons and interventional
pain specialists to respect these specific indications to work towards the welfare
of the patient. In my experience, it is the surgeons who refer patients to me
for pain and I refer patients to them if surgery is needed. I simply put myself
in the patients' shoes," Dr Vas explains.
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"Judicious
and intelligent use can relieve 70-80 per cent of all pain"
Dr P Saraswati Devi
Head, Department of Anaesthetics and Pain Relief
Kidwai Memorial Cancer Hospital, Bangalore
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A patient with vertebral collapse, either due to osteoporosis
or bone metastasis, will be treated with vertebroplasty done through a needle,
when bone cement is injected to reconstruct the vertebra, otherwise he would
undergo major surgery. It is important to remember that most pain can be relieved
by simple pharmacological methods; the WHO 3-step analgesic ladder is the gold
standard for pain management. "Judicious and intelligent use of this ladder
can relieve 70-80 per cent of all pain," says Dr P Saraswati Devi, Professor
and Head, Department of Anaesthetics and Pain Relief, Kidwai Memorial Cancer
Hospital, Bangalore.
Centres In Interventional Pain Management
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"Interventions
are certainly the mainstay of treatment in chronic pain"
- Prof GP Dureja
Head, Indian Spinal Injuries Centre, New Delhi
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A pain clinic is the place of convergence for all patients
suffering from pain, irrespective of the aetiology of pain, medical, surgical,
orthopaedic or traumatic oncological. The only criterion is that a patient has
to complain of pain for more than three to six months. Interventional pain management
techniques are still in their infancy in India and very few dedicated centres
exist.
The first department of pain medicine was started in a corporate
hospital, Indian Spinal Injuries Centre, New Delhi in 2006, with Prof GP Dureja
as head. "Interventions are certainly the mainstay of treatment in chronic
pain and there will be more such dedicated centres in future," predicts
Prof Dureja. Besides Mumbai and New Delhi, some centres in the South are NIMHANS,
Bangalore, Sri Chitrai Tirunal Medical Centre, Thiruvananthapuram and CMC, Vellore.
What Does The Future Hold?
In this fast moving society seeking fast track treatment of
illnesses and pain, pain management has a great future ahead, predict experts.
Technology helps in locating precisely the cause of pain as well as targeting
the drug at the site of origin of pain. Of course, one cannot overemphasise
the role of a good clinical examination in diagnosing the cause of pain. Special
skills of an anaesthesiologist in blocking nerves and reaching the sites in
the spinal cord make him an ideal pain physician. "However, it is now up
to him to develop the super speciality of pain medicine so that it is of great
help to the millions of people suffering from chronic intractable pain syndromes
in improving their quality of life," Dr Dureja maintains.
Pain is a major health hazard, expected to rise with ageing population and lifestyle
changes. The future will make greater use of relaxation therapies for managing
the psycho-emotional component of pain with non-drug therapies, and with newer
and more specific pain medications (many undergoing trials) and equipment to
locate pain generators, and modify pain sensation for those pains which are
not useful as a warning. "Specific drugs will replace the present crop
of painkiller medications. Newer drug delivery systems and regional drug delivery
of medication systems will develop, which will be cheaper than the present systems,"
Dr Choudhary adds.
Pain as a symptom overrides all other symptoms: so much so, that it has been
included as the 'fifth vital sign' while evaluating a patient's parameters.
Unfortunately, pain is very often under-diagnosed, consequently under-treated.
"It is very essential that all doctors are sensitised to this important
problem, if they are to make any impact on the patient's quality of life,"
Dr Devi says.
"The approach should be more patient oriented than disease oriented. This
requires significant interaction and seamless co-operation between various specialists
and family physicians with the patient's physical and mental well-being the
ultimate aim. It requires a team effort involving pain specialists, psychologists,
physiotherapists and palliative care personnel," Dr Vas opines.
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"Pain
management is a vast ocean and there are several explorers out at sea"
- Dr Edmund DCouto
Head, Dept of Physical Medicine and Rehabilitation
Kovai Medical Centre and Hospital, Coimbatore
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"Pain management is a vast ocean and there are several
explorers out at sea. Newer and more accurate diagnostic techniques mean better
chances of identification of the cause and as a consequence, development of
more specific therapies in pain management. Right now and more so in the future
I think every type of pain can be managed-except probably of broken hearts,"
Dr Edmund D'Couto, Consultant Physiatrist and Head, Department of Physical Medicine
and Rehabilitation, Kovai Medical Centre and Hospital, Coimbatore.
According to Dr D'Couto, "Pain can be of varied aetiology and when we talk
about pain management we do not generally talk about the acute pain of trauma,
but are generally referring to chronic pain." This can be either from an
identifiable and rectifiable condition or an identifiable, but not rectifiable
condition or not physically identifiable condition.
Identifiable and rectifiable conditions are ones like chronic low back pain
of poor postures, mechanical low back pain, myofacial pain involving the neck
and back etc. Identifiable but not rectifiable conditions-conditions like pain
of metastatic carcinoma, which is in late stages, intractable pain due to nerve
injuries etc. Not physically identifiable condition: like pain of psychogenic
origin or pain as a psychosomatic disorder. Here treatment would involve more
of psychiatric therapy.
"I prefer a comprehensive therapy using drugs, physical modalities like
diathermy, bio-feedback, laser and exercises. The advantage is that it offers
a permanent and lasting solution, addressing the basic cause of the pain and
not just masking the pain. The disadvantage-not a passive therapy administered
by the physician, but involves the active participation of the patient in the
treatment process," says Dr D'Couto.
There is a palpable drift away from symptomatic treatment
to more comprehensive and aetiology-directed medicine and this trend is likely
to increase among patients and practitioners alike. Hence, technologies supporting
this trend will gain more importance.
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Nerve blocking: This procedure is used when
there is a lot of scar tissue around the nerves in the spinal canal after
a spine surgery or disc prolapse. A fine hair-like tube called catheter
is passed into the spinal canal into the epidural space. Injections are
given through the catheter to dissolve the scars around inflamed or entrapped
nerves, which relieves the pain. With the advent of Radiofrequency Ablation,
permanent nerve blocking has become safe and more effective.
Fluoroscopy or CT guided interventions: This
technique in spinal pain has resulted in precision delivery of drugs to
the targeted site. This has improved the results of interventions significantly.
Moreover, they are cheap compared with spine surgery and do not require
hospital admission.
Adhesiolysis: This is generally used in pelvic
pain caused by adhesions following surgery, radiotherapy or infection.
Therapeutic nerve ablation procedures: Techniques
with radiofrequency energy are particularly useful in many types of back
and neck pains as well as in other neuropathic pain conditions. Using
radiofrequency to cause a controlled destruction of inflamed nerves relieves
pain over a long period of time (till the nerve regrows).
Intra Muscular Stimulation (IMS): It is a
diagnostic and therapeutic technique for most varieties of muscular pain.
Hair-thin 32-G acupuncture needles are introduced into the muscles, causing
an initial tightening and a subsequent relaxation. This induces a prolonged
relaxation of the deep muscles.
Continuous nerve plexus blocks with indwelling
catheters: This technique is for any chronic pain condition which
has evolved over months and years. Its treatment may involve injection
of calming medications over weeks rather than a single injection. This
technique can be used for many painful conditions of the upper and lower
extremities.
Intrathecal pump implants and spinal cord stimulation:
These sophisticated therapies are very useful techniques for patients
with intractable pains like those of cancer, failed back surgery, demyelinating
disorders, arachnoiditis, severe spasticity from cerebral palsy, spinal
cord injuries, refractory phantom limb pain and patients with refractory
angina. Intrathecal drug delivery with an implantable computerised or
gas driven pumps (Medtronics, Codman) are now available in India. Implantation
of sophisticated titanium pumps for continuous intrathecal infusion of
morphine clonidine and baclofen has revolutionised the outlook for sufferers
of chronic intractable pains. They are particularly useful in patients
of long-standing back pain, where surgery is not possible or has failed
and medication difficult with risks of renal problems with NSAIDs and
addiction with opioids. Intrathecal pumps and spinal cord stimulators
are a boon to this unfortunate group with a long life expectancy but a
life full of pain.
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With inputs from Jayata Sharma
ehm@expresshealthcaremgmt.com
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