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Home > Cover Story

Private sector must prioritise research

Soumya Viswanathan - Mumbai

In the medical circles, as far as research goes, the popular joke is -- publish or perish. Papers are therefore published, generally "inspired" by articles in foreign journals. But prospective medical research, which is pre-planned research, takes a back seat over clinical work in India.

The numbers may have attracted multi-national contract research organisations but Indian healthcare institutions are not impressed. While government has the numbers and no money, private has low numbers and the drive to make money and therefore neglects research, feel experts.

Those voicing their dissatisfaction over existing medical research scenario say whatever little that is coming is from the government side and private sector, inspite of being the more dominating one with 80 per cent market, is hardly contributing towards it. Even in Mumbai there is hardly any research being conducted since most hospitals here employ part-time consultants.

Medical research in private hospitals today is mostly retrospective analysis of established facts. Large proportion of the research that is published is retrospective research where patient records are analyzed and data collected. Dr Harish Nadkarni, Mumbai-based ISO expert agrees. "Medical research today is only statistical analysis of cases. The studies are done only conform to established international outcomes," he says.

And there are reasons why experts stress that hospitals prioritise prospective research. Says Dr Murad Lala, consultant surgical oncologist, Hinduja Hospital, "Only 5 per cent of world’s population suffers from oral cancer as compared to 30 per cent of Indians. Research therefore must come from here." Agrees Dr Subbiah Arunachalam, distinguished fellow, M S Swaminathan Research Foundation, Chennai, "The 90/10 issue in medicine is known to all. Ninety per cent of what the US spends accounts for 10 per cent of the world’s diseases. But 90 per cent of diseases that India suffers from attracts less than ten per cent of funds. Spending in medicine and agriculture must therefore be local."

Dr Girish Nair, project director, Cardiac Research Academy (CRA), Bangalore says, "Cardiovascular research in the developed countries has built a scientific base for defining risk and recognising when to intervene. Such data has also been useful for developing constructive public health policies and programmes. With the CVD epidemic in India becoming apparent, local research is required to build a scientific base for defining the CVD risk and recognising when to intervene." The CRA in association with Heart Centre which funded Rs 3 lakh studied the heart status of 182 policemen. The result submitted to the state government has evoked an assurance of immediate release of funds for police personnel in case of contingency. But such initiatives are few and far between.

While experts insist that the industry must work towards this, there are some hurdles in making it happen. "A problem about good quality prospective research is balancing the responsibility of patient care and research. In almost all hospitals in India, the work load on the consultants in terms of patient care is very heavy and they are not able to dedicate adequate time to research," says Dr Arun Goel, sr surgical oncologist, Dharamshila Cancer Hospital.

Private hospitals may have the advantage of fewer patients and therefore enough time to carry out research but the disadvantage of low numbers. Experts feel one solution is to have multi-centric studies. Dr Nandini Mundkur, chief executive, Bangalore Children’s Hospital and Research Centre is in favour of encouraging multi-centric studies to make it meaningful rather than accept those funded by the pharma industry as the outcome is generally biased. The hospital has signed a MoU with Sir Dorabji Tata Centre for Research in Tropical Diseases and the Center for Human Genetics to conduct multi-centric studies in childhood autusim.

The Indian Cooperative Oncologists’ Network is one such initiative made by oncologists across the country to conduct muti-centric trials. ’’In India, such bodies don’t work because of bloated egos and the insecurity of "losing a patient," says an oncologist.

Then there comes the hospital’s responsibility to provide infrastructure, one of the reasons for absence of adequate research, feel some. Says Dr Naresh Trehan, Escorts Heart Institute, "Most of the hospitals in India neither have that kind of money nor the physical resources. So their work is restricted."

V R Joshi, director, medical research, Hinduja Hospital says quality research needs resources both in terms of manpower, laboratory facilities and related infrastructure. "Not all hospitals can boast of this," he says.

Even after everything is made available to the researchers, it is the mind-set which must change feel some. "If medical curriculum gives importance to training in research then a handful of doctors may show interest. Recently the Dept of Science and Technology offered research scholarships for 30 students but only enrolled 3 or 4 because they got only so many candidates," says Dr V Mohan of M V Diabetes Research Centre, Chennai.

Says Dr Arunachalam, "It is for a doctor to carry out research if he wants to perform well. At a senior level especially, it is very important to do so."

Finally, the advantage. Cutting edge research generates intellectual property that may add to the country’s prosperity. The last word -- Attempts to reduce clinical work load and promote research are required to improve the quality of research.

A rough indicator of research:

Publications as listed on Pubmed:

Multi-speciality Hospitals:

Hinduja Hospital 1985-200285
Jaslok1988-200282
Amrita Institute of Medical Sciences1994-200219
New Eye Hospitals:
Aditya Jyottill 20022
LVPEItill 20022
Speciality Hospitals:
Wockhardt Hospital1989-20026
Escorts Hospital1993-200214
SankaraNetralaya1987-2002104
John Hopkins200259

(With inputs from Vijaya K in Bangalore and Nidhi Srivastava in Delhi)
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